
Semax
An ACTH fragment with the hormonal activity stripped out and the neurological activity kept — the best-known nootropic peptide there is.
An ACTH-derived nootropic that enhances focus, memory consolidation and neuroprotection, a favourite among biohackers.
Concentrations · 1 vial
from R 4005mg selected — in stock and shipping now.
About Semax
Semax is derived from ACTH(4-10), a fragment of adrenocorticotropic hormone, modified so that the hormonal effects are gone and what remains acts on the brain. Like Selank it came out of the Russian Academy of Sciences and has been in clinical use there for decades, in contexts ranging from cognitive impairment to stroke recovery.
The research interest that brings people here is narrower than the clinical one: focus, memory consolidation and neuroprotection, mediated in part through BDNF — brain-derived neurotrophic factor, the signalling protein most associated with neuroplasticity. It is the most widely used nootropic peptide and the reference point that Adamax, its modified successor, is measured against.
What it’s researched for
Research context, not medical advice. Everything we sell is supplied for research purposes.
Focus and attention
The effect most people are after, and the one that made Semax the default nootropic peptide well before the others arrived.
Memory consolidation
Studied for learning and memory formation rather than recall alone, which is consistent with a BDNF-mediated mechanism.
Neuroprotection
The basis of its Russian clinical use, in contexts including stroke recovery and cognitive decline.
Reconstitution and storage
The 5mg vial with 2 mL of bacteriostatic water gives 2.5mg/mL. Semax, like Selank, is commonly used intranasally in research settings; the vial we supply is lyophilised powder for reconstitution. Unopened vials are stable at room temperature in transit but belong in a fridge once they arrive, and out of a parked car in a Highveld summer.
Questions we get about Semax
Often bought with it
Order Semax in South Africa
Everything ships from Johannesburg, nationwide. Message us on WhatsApp and we’ll confirm stock, pricing and delivery before you pay a cent.


