DSIP
A peptide named for what it was found doing — inducing delta wave sleep, the deepest stage there is.
Delta sleep-inducing peptide, studied since 1977 for deep sleep and the sleep-wake cycle, with mixed results in people.
- Also known as
- Delta sleep-inducing peptide
- Class
- Nine-amino-acid neuropeptide, first isolated in 1977
- Evidence
- Early human studies
- FDA
- Not approved
- WADA 2026
- Not named; likely covered by S0 (substances not approved for human use anywhere are prohibited at all times)
Concentrations · 1 vial
from R 2905mg selected — in stock and shipping now.
About DSIP
Delta Sleep-Inducing Peptide was isolated in the 1970s from the blood of sleeping rabbits, and named for the effect it produced: an increase in delta wave activity, the slow-wave stage where physical recovery, growth hormone release and memory consolidation concentrate.
That focus on sleep quality rather than sleep onset is what distinguishes it from most sleep aids. DSIP is not researched as a sedative; the interest is in the architecture of sleep once you are in it, which is why it is usually chosen by people who fall asleep fine but wake unrefreshed. It also has a research interest in circadian regulation more broadly, which is why it appears alongside Epithalon in some protocols.
Specifications
Evidence level: Early human studies · Small, older studies with inconsistent results.
- Sequence
- Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu (nine amino acids), first described in 1977
- Formula
- C35H48N10O15 PubChem ↗
- Molecular weight
- 848.8 g/mol
- CAS number
- 62568-57-4
What it’s researched for
Research context, not medical advice. Everything we sell is supplied for research purposes.
Delta wave sleep
The deep, slow-wave stage where physical recovery and growth hormone release concentrate — the stage the compound is named for.
Sleep-wake regulation
Studied for circadian rhythm rather than sedation, which is why it is often paired with Epithalon in longevity protocols.
Recovery
The reason it turns up in athletic protocols: growth hormone release is largest in deep sleep, so sleep quality and recovery are the same conversation.
What the research does not show
The limits of the evidence, stated as plainly as the findings.
- A reliable effect on sleep. Small human studies in the 1980s gave mixed results, and a 2006 review called its role “a still unresolved riddle”.
Reconstitution and storage
The 5mg vial with 2 mL of bacteriostatic water gives 2.5mg/mL. Unopened vials are stable at room temperature in transit but belong in a fridge once they arrive, and out of a parked car in a Highveld summer.
Questions we get about DSIP
Sources
- Schoenenberger GA, Monnier M. Characterization of a delta-electroencephalogram (-sleep)-inducing peptide. Proceedings of the National Academy of Sciences of the United States of America, 1977.
- Kovalzon VM, Strekalova TV. Delta sleep-inducing peptide (DSIP): a still unresolved riddle. Journal of Neurochemistry, 2006.
- Schneider-Helmert D. Efficacy of DSIP to normalize sleep in middle-aged and elderly chronic insomniacs. European Neurology, 1986.
Order DSIP in South Africa
Everything ships from Johannesburg, nationwide. Add it to your order slip, send the slip on WhatsApp, and we’ll confirm stock, pricing and delivery before you pay a cent.