Thymosin Alpha-1
A thymus-derived peptide that tunes the immune response rather than simply amplifying it.
An immune-modulating thymic peptide that supports T-cell maturation, approved outside the US for hepatitis B.
- Also known as
- Thymalfasin; Zadaxin
- Class
- 28-amino-acid thymic peptide (immune modulator)
- Evidence
- Approved medicine
- FDA
- Not approved in the US
- WADA 2026
- Not named
Concentrations · 1 vial
from R 65010mg selected — in stock and shipping now.
About Thymosin Alpha-1
Thymosin Alpha-1 is a 28-amino-acid peptide produced by the thymus, the gland that trains T-cells and that atrophies steadily from adolescence onward. It is one of the most clinically established compounds in this catalogue: it is approved in a number of countries as an immune modulator and has been used clinically for decades, particularly in chronic viral infection and as a vaccine adjuvant.
The word to hold onto is modulator. It is studied for activating T-cells and dendritic cells and for restoring balance to an immune response, not for stimulating the immune system indiscriminately — which matters, because indiscriminate stimulation is the last thing you want in a system that can overreact. That distinction is why it appears in protocols for chronic immune problems rather than as a seasonal supplement.
Specifications
Evidence level: Approved medicine · Approved outside the US, mainly for hepatitis B.
- Structure
- 28 amino acids, N-terminally acetylated
- Formula
- C129H215N33O55 PubChem ↗
- Molecular weight
- 3108.3 g/mol
- CAS number
- 62304-98-7
What it’s researched for
Research context, not medical advice. Everything we sell is supplied for research purposes.
T-cell activation
The core mechanism: maturation and activation of T-cells, the function the thymus itself performs and loses with age.
Immune modulation
Restoring balance rather than amplifying response, which is the distinction that makes it suitable for chronic rather than acute use.
Chronic infection
Where most of the clinical literature sits, alongside its use as a vaccine adjuvant.
What the research does not show
The limits of the evidence, stated as plainly as the findings.
- US approval. Its approvals are elsewhere, mainly for hepatitis B.
Reconstitution and storage
The 10mg vial with 2 mL of bacteriostatic water gives 5mg/mL. Unopened vials are stable at room temperature in transit but belong in a fridge once they arrive, and out of a parked car in a Highveld summer.
Questions we get about Thymosin Alpha-1
Sources
- Naing C, Ni H, et al. Thymosin-ɑ1 for people with chronic hepatitis B. The Cochrane Database of Systematic Reviews, 2026.
- Wu X, Jia J, et al. Thymosin alpha-1 treatment in chronic hepatitis B. Expert Opinion on Biological Therapy, 2015.
- Wu J, Zhou L, et al. The efficacy of thymosin alpha 1 for severe sepsis (ETASS): a multicenter, single-blind, randomized and controlled trial. Critical Care, 2013.
Often bought with it
Order Thymosin Alpha-1 in South Africa
Everything ships from Johannesburg, nationwide. Add it to your order slip, send the slip on WhatsApp, and we’ll confirm stock, pricing and delivery before you pay a cent.