SLU-PP-332
A compound that activates the same receptors exercise does — the reason it gets called exercise in a bottle, and the reason that name oversells it.
An ERR agonist studied in mice as an “exercise mimetic” for endurance and fat oxidation. There is no human data yet.
- Class
- Small-molecule ERR agonist, studied as an “exercise mimetic” (not a peptide)
- Evidence
- Animal and cell studies
- FDA
- Not approved
- WADA 2026
- Not named; likely covered by S0 (substances not approved for human use anywhere are prohibited at all times). Anti-doping labs have published methods to detect it.
Concentrations · 1 vial
R 4005mg selected — in stock and shipping now.
About SLU-PP-332
SLU-PP-332 is an ERR agonist: it activates the estrogen-related receptors, a family of transcription factors that exercise itself switches on. Downstream of that are mitochondrial biogenesis, fat oxidation and endurance — which is why the early research generated headlines about a compound that reproduces the metabolic benefits of training.
The honest version is narrower. What the research shows is activation of the same pathway, with measurable effects on mitochondrial activity and fat oxidation in animal models. It does not build the musculoskeletal adaptations, cardiovascular capacity or anything else training gives you. It is one of the newest compounds in the catalogue and its literature is correspondingly thin compared to something like GHK-Cu.
Specifications
Evidence level: Animal and cell studies
- Formula
- C18H14N2O2 PubChem ↗
- Molecular weight
- 290.3 g/mol
- CAS number
- 303760-60-3
What it’s researched for
Research context, not medical advice. Everything we sell is supplied for research purposes.
Mitochondrial biogenesis
The ERR pathway drives new mitochondria, which is the mechanism behind most of what SLU-PP-332 is studied for.
Fat oxidation
Researched for a shift toward burning fat for fuel rather than for appetite suppression, which puts it in a different bracket from the GLP-1s.
Endurance
The endpoint that generated the "exercise mimetic" framing. Worth reading with the caveat that it is a pathway effect, not a replacement for training.
What the research does not show
The limits of the evidence, stated as plainly as the findings.
- Any human data.
- That it can replace exercise.
Reconstitution and storage
The 5mg vial with 2 mL of bacteriostatic water gives 2.5mg/mL. Unopened vials are stable at room temperature in transit but belong in a fridge once they arrive, and out of a parked car in a Highveld summer.
Questions we get about SLU-PP-332
Sources
- Billon C, Sitaula S, et al. Synthetic ERRα/β/γ Agonist Induces an ERRα-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity. ACS Chemical Biology, 2023.
- Okda HE, Zhao P, et al. Chemical optimization of the exercise mimetic SLU-PP-332 enables insight into estrogen-related receptor signaling. International Journal of Biological Macromolecules, 2026.
- Möller T, Krug O, et al. In Vitro Metabolism and Analytical Characterization of SLU-PP-332 and SLU-PP-915: Novel Pan-ERR Agonists With Doping Potential. Rapid Communications in Mass Spectrometry, 2026.
Often bought with it
Order SLU-PP-332 in South Africa
Everything ships from Johannesburg, nationwide. Add it to your order slip, send the slip on WhatsApp, and we’ll confirm stock, pricing and delivery before you pay a cent.