GHRP-6
One of the original growth hormone secretagogues, and still the one used when appetite is the point rather than a side effect.
A growth hormone-releasing peptide that triggers GH release and raises appetite, studied in short human tests of GH reserve.
- Also known as
- Growth hormone-releasing hexapeptide
- Class
- Growth hormone secretagogue (ghrelin receptor agonist)
- Evidence
- Early human studies
- FDA
- Not approved
- WADA 2026
- Prohibited at all times under S2 (named)
Concentrations · 1 vial
from R 25010mg selected — in stock and shipping now.
About GHRP-6
GHRP-6 is a hexapeptide that mimics ghrelin at the growth hormone secretagogue receptor, prompting the pituitary to release a pulse of growth hormone. It was among the first of its class to be studied and remains a reference point for the ones that followed. Its distinguishing feature is a strong effect on appetite — pronounced enough that it is the reason some people choose it and the reason others choose Ipamorelin instead.
In practice that makes GHRP-6 a lean-mass tool rather than a fat-loss one. It is most often researched in bulking and recovery contexts, where eating enough is the constraint, and it is frequently paired with a GHRH analogue such as CJC-1295, on the reasoning that a secretagogue and a releasing hormone acting together produce a larger pulse than either alone.
Specifications
Evidence level: Early human studies · Human studies are short diagnostic and pharmacokinetic tests.
- Sequence
- His-D-Trp-Ala-Trp-D-Phe-Lys-NH2 (six amino acids)
- Formula
- C46H56N12O6 PubChem ↗
- Molecular weight
- 873.0 g/mol
What it’s researched for
Research context, not medical advice. Everything we sell is supplied for research purposes.
Growth hormone release
The core research interest: a pulsatile GH release that follows the body's own rhythm rather than replacing it, which is the argument for secretagogues over exogenous HGH.
Appetite
A marked increase in hunger, usually within twenty minutes. Useful in a lean-mass phase, and the main reason to pick a different secretagogue if you are cutting.
Lean mass protocols
Commonly stacked with a GHRH analogue and run alongside a surplus, where the appetite effect helps rather than hinders.
What the research does not show
The limits of the evidence, stated as plainly as the findings.
- Trials of repeated use in people. The human studies are short tests of growth hormone release.
- Approval for any use.
Reconstitution and storage
The 10mg vial reconstituted with 2 mL of bacteriostatic water gives 5mg/mL. Unopened vials are stable at room temperature in transit but belong in a fridge once they arrive, and out of a parked car in a Highveld summer.
Questions we get about GHRP-6
Sources
- Bowers CY, Momany FA, et al. On the in vitro and in vivo activity of a new synthetic hexapeptide that acts on the pituitary to specifically release growth hormone. Endocrinology, 1984.
- Bowers CY. Unnatural growth hormone-releasing peptide begets natural ghrelin. The Journal of Clinical Endocrinology and Metabolism, 2001.
- Cabrales A, Gil J, et al. Pharmacokinetic study of Growth Hormone-Releasing Peptide 6 (GHRP-6) in nine male healthy volunteers. European Journal of Pharmaceutical Sciences, 2013.
- World Anti-Doping Agency. International Standard Prohibited List 2026. WADA, 2025.
Order GHRP-6 in South Africa
Everything ships from Johannesburg, nationwide. Add it to your order slip, send the slip on WhatsApp, and we’ll confirm stock, pricing and delivery before you pay a cent.